NFC West
Vegas gives the 49ers the highest expected score in the NFC West this week at about 26.8 points as 3-point favorites; the Cardinals are lowest at about 19.5. By EPA per play, the 49ers have the group's best offense (#2 in the NFL) and the Seahawks the best defense (#2).
NFC West standings
| Team | Record |
|---|---|
| San Francisco 49ers | 6-0 |
| Seattle Seahawks | 3-3 |
| Arizona Cardinals | 2-4 |
| Los Angeles Rams | 2-4 |
Week 7 matchups
| Team | Opponent | Kickoff | Spread | Total | Team expected pts |
|---|---|---|---|---|---|
| Cardinals | vs Broncos | Sun, Oct 25, 4:05 PM ET | +4.5 | 43.5 | 19.5 |
| Rams | @ Raiders | Sun, Oct 25, 4:25 PM ET | -4.5 | 47.5 | 26 |
| 49ers | @ Falcons | Sun, Oct 25, 1:00 PM ET | -3 | 50.5 | 26.8 |
| Seahawks | vs Chiefs | Sun, Oct 25, 8:20 PM ET | -2.5 | 42.5 | 22.5 |
Spread is from that team's side (minus = favored). Expected points come from the Vegas total and spread. Lines: nflverse schedule data.
Top projected players this week
From BFN Hot Picks (PPR scoring), our own projection built from workload, Vegas totals, matchups and injury reports.
- Cardinals: Jacoby Brissett (QB, 19.5 pts, range 10.1-26.1); Trey McBride (TE, 16.5 pts, range 6.7-28)
- Rams: Puka Nacua (WR, 25.5 pts, range 9.4-37.3); Matthew Stafford (QB, 23.9 pts, range 12.4-32.1); Kyren Williams (RB, 21.3 pts, range 10.2-32.8)
- 49ers: Brock Purdy (QB, 25.6 pts, range 13.3-34.3); Christian McCaffrey (RB, 22.3 pts, range 10.7-34.4); George Kittle (TE, 15.3 pts, range 6.3-26)
- Seahawks: Jaxon Smith-Njigba (WR, 22.5 pts, range 8.3-32.8)
Advanced stats: EPA ranks through week 6
| Team | Offense EPA/play | Offense success rate | Defense EPA allowed |
|---|---|---|---|
| 49ers | +0.18 (#2) | 52% (#1) | -0.06 (#5) |
| Rams | +0.04 (#12) | 47% (#6) | -0.02 (#14) |
| Cardinals | -0.01 (#18) | 46% (#11) | +0.09 (#28) |
| Seahawks | -0.07 (#26) | 42% (#22) | -0.11 (#2) |
EPA = expected points added per play (# = NFL rank; for defense, less allowed ranks higher). Computed by Breaking Fantasy News from nflverse play-by-play.
Latest NFC West news
- I Hate Fantasy Football! – Week 7 Waivers Razzball Football · October 20, 2026Fantasy impact: No direct fantasy action needed.
- With Matthew Stafford's next loss, he ties Vinny Testaverde for the most QB losses ever ProFootballTalk · October 20, 2026Fantasy impact: Results story; limited roster impact.
- ‘They’re Getting Bullied’ — Patriots Legends Julian Edelman, Rob Gronkowski Give Sean McVay’s Rams The Blueprint To Climb Out of 2-4 Hole Pro Football Network · October 20, 2026Fantasy impact: No direct fantasy action needed.
- The 49ers are the Super Bowl favorites … but there’s a catch SB Nation NFL · October 20, 2026Fantasy impact: No direct fantasy action needed.
- Rams’ division title odds crushed after Monday night Yahoo Sports NFL · October 20, 2026Fantasy impact: Results story; limited roster impact.
- Mike Evans injury update: WR avoids long-term injury, but how will 49ers fare if he misses time? CBS Sports NFL · October 20, 2026Fantasy impact: Monitor status; backups gain value if he misses time.
- Rams plan to replace K Blake Grupe in next day or two ProFootballTalk · October 20, 2026Fantasy impact: Monitor status; backups gain value if he misses time.
- U2 will headline halftime show for Packers-Rams Thanksgiving eve game on Netflix Yahoo Sports NFL · October 20, 2026Fantasy impact: No direct fantasy action needed.
- ‘I’ve Dealt With an Achilles Injury,’ ‘The Pain Is So Intense’ — Ex-49ers CB ‘Feels Bad’ for Mike Evans After Frustrating MNF Blow Pro Football Network · October 20, 2026Fantasy impact: Target/touch shares shift on both teams. Re-check depth charts.
- Brock Purdy is doing it all for the 49ers. Now they need to do something for him The Athletic NFL · October 20, 2026Fantasy impact: Monitor status; backups gain value if he misses time.
- Why the Seahawks don’t need to bench Sam Darnold Yahoo Sports NFL · October 20, 2026Fantasy impact: Role change — adjust weekly rankings for everyone in that room.
- NFL Week 6 betting: 5 biggest storylines, including how Rams upset loss shook up the odds Yahoo Sports NFL · October 20, 2026Fantasy impact: Results story; limited roster impact.
- Pre-Snap Reads: Will a big trade fix the Seahawks’ problems on offense? Yahoo Sports NFL · October 20, 2026Fantasy impact: Target/touch shares shift on both teams. Re-check depth charts.
- NFC West Recap: 49ers continue to distance themselves; Rams and Seahawks lose Yahoo Sports NFL · October 20, 2026Fantasy impact: Results story; limited roster impact.
- Dan Quinn denies confusion after viral fourth-down clip in Commanders loss to 49ers CBS Sports NFL · October 20, 2026Fantasy impact: Results story; limited roster impact.
- PFT's Week 7 2026 NFL power rankings Yahoo Sports NFL · October 20, 2026Fantasy impact: No direct fantasy action needed.
- How long is Terry McLaurin out? Latest updates on Commanders WR's knee injury Yahoo Sports NFL · October 20, 2026Fantasy impact: Monitor status; backups gain value if he misses time.
- Mike Evans Dealing With Achilles Tendonitis Draft Sharks Shark Bites · October 20, 2026Fantasy impact: Results story; limited roster impact.
- NFL Week 6 Recap: Washington Commanders 17, San Francisco 49ers 23 PFF · October 20, 2026Fantasy impact: Results story; limited roster impact.
- Rams ‘dream season’ being derailed by poor play and injuries Yahoo Sports NFL · October 20, 2026Fantasy impact: Monitor status; backups gain value if he misses time.
Headlines link to the original publisher. Fantasy impact notes are written by Breaking Fantasy News.