San Francisco 49ers
San Francisco 49ers fantasy outlook
The San Francisco 49ers (NFC West) are 6-0 this season.
Week 7: at the Atlanta Falcons, Sun, Oct 25, 1:00 PM ET. Vegas expects 49ers to score about 26.8 points as a 3-point favorite.
On BFN Hot Picks this week: Brock Purdy (QB #3, 25.6 projected PPR pts); Christian McCaffrey (RB #2, 22.3 projected PPR pts); George Kittle (TE #3, 15.3 projected PPR pts); Eddy Pineiro (K #11, 8.1 projected PPR pts); 49ers D/ST (DST #13, 10 projected PPR pts).
Injury report (fantasy positions):
- Mike Evans (WR) -- Out, Achilles
- Demarcus Robinson (WR) -- IR
- Christian Kirk (WR) -- IR
- Deebo Samuel Sr. (WR) -- Out, Hamstring
- Jake Tonges (TE) -- IR
- Isaac Guerendo (RB) -- PUP
- Ricky Pearsall (WR) -- IR
- Kurtis Rourke (QB) -- Out, Coach's Decision
- De'Zhaun Stribling (WR) -- IR
Depth chart starters: QB: Brock Purdy · RB: Christian McCaffrey, Kaelon Black · WR: Mike Evans, Deebo Samuel, Brandin Cooks · TE: George Kittle.
Advanced stats through week 6 (# = NFL rank; for defense, less allowed ranks higher):
| EPA/play | Success rate | Pass EPA | Rush EPA | |
|---|---|---|---|---|
| Offense | +0.18 #2 | 52% #1 | +0.33 #1 | -0.02 #6 |
| Defense | -0.06 #5 | 43% #15 | +0.03 #14 | -0.20 #3 |
EPA = expected points added per play; success rate = share of plays that gained enough to stay on schedule. Data: nflverse play-by-play.
Latest 49ers news
- The 49ers are the Super Bowl favorites … but there’s a catch SB Nation NFL · October 20, 2026Fantasy impact: No direct fantasy action needed.
- Mike Evans injury update: WR avoids long-term injury, but how will 49ers fare if he misses time? CBS Sports NFL · October 20, 2026Fantasy impact: Monitor status; backups gain value if he misses time.
- ‘I’ve Dealt With an Achilles Injury,’ ‘The Pain Is So Intense’ — Ex-49ers CB ‘Feels Bad’ for Mike Evans After Frustrating MNF Blow Pro Football Network · October 20, 2026Fantasy impact: Target/touch shares shift on both teams. Re-check depth charts.
- Brock Purdy is doing it all for the 49ers. Now they need to do something for him The Athletic NFL · October 20, 2026Fantasy impact: Monitor status; backups gain value if he misses time.
- NFC West Recap: 49ers continue to distance themselves; Rams and Seahawks lose Yahoo Sports NFL · October 20, 2026Fantasy impact: Results story; limited roster impact.
- Dan Quinn denies confusion after viral fourth-down clip in Commanders loss to 49ers CBS Sports NFL · October 20, 2026Fantasy impact: Results story; limited roster impact.
- PFT's Week 7 2026 NFL power rankings ProFootballTalk · October 20, 2026Fantasy impact: No direct fantasy action needed.
- How long is Terry McLaurin out? Latest updates on Commanders WR's knee injury Yahoo Sports NFL · October 20, 2026Fantasy impact: Monitor status; backups gain value if he misses time.
- Mike Evans Dealing With Achilles Tendonitis Draft Sharks Shark Bites · October 20, 2026Fantasy impact: Results story; limited roster impact.
- NFL Week 6 Recap: Washington Commanders 17, San Francisco 49ers 23 PFF · October 20, 2026Fantasy impact: Results story; limited roster impact.
- Kyle Shanahan: Eddy Pineiro has got to make his extra points ProFootballTalk · October 20, 2026Fantasy impact: No direct fantasy action needed.
- NFL power rankings Week 7: Do struggling Rams, Seahawks drop out of top 10? Yahoo Sports NFL · October 20, 2026Fantasy impact: No direct fantasy action needed.
- ‘Why Even Try to Lie,’ ‘You’re So Fired’ — NFL Fans Not Buying Commanders HC Dan Quinn’s Explanation For Viral Moment of Confusion vs. 49ers Pro Football Network · October 20, 2026Fantasy impact: No direct fantasy action needed.
- Kyle Shanahan: Mike Evans injury is not a long-term thing, hopeful he can play Sunday ProFootballTalk · October 20, 2026Fantasy impact: Monitor status; backups gain value if he misses time.
- ‘Crazy Stuff,’ ‘What an Insane Decision’ — NFL Fans Take Issue With Refs Steering Clear of Penalizing 49ers’ Fred Warner vs. Commanders Pro Football Network · October 20, 2026Fantasy impact: No direct fantasy action needed.
- ‘Do You Even Watch Football?’ ‘Better Than (Patrick) Mahomes’ — NFL Fans Get Vocal As Ryan Clark Kickstarts Brock Purdy MVP Debate Pro Football Network · October 20, 2026Fantasy impact: No direct fantasy action needed.
- George Kittle Delivers Another TE1 Week on Season-High 8 Targets Draft Sharks Shark Bites · October 20, 2026Fantasy impact: Results story; limited roster impact.
Headlines link to the original publisher. Fantasy impact notes are written by Breaking Fantasy News.
More NFC West: Arizona Cardinals · Los Angeles Rams · Seattle Seahawks